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T7740 |
Protease-Activated Receptor-4 diTFA
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Protease-Activated Receptor-4 diTFA(245443-52-1(free base)) |
Protease-activated Receptor
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Protease-Activated Receptor-4 diTFA,2454 is the proteinase-activated receptor-4 (PAR4)agonist |
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T38836L |
Protease-Activated Receptor-1, PAR-1 Agonist acetate
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Protease-activated Receptor
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Protease-Activated Receptor-1, PAR-1 Agonist acetate is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist acetate corresponds to PAR1 tethered ligand and whi... |
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T7513 |
Protease-Activated Receptor-2, amide
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SLIGKV-NH2 |
Protease-activated Receptor
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Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of PAR2 (IC50 : 10.4 M) |
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T38836 |
Protease-Activated Receptor-1, PAR-1 Agonist
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Protease-Activated Receptor-1 (PAR-1) Agonist, a selective peptide, activates the PAR-1 receptor by mimicking the specific actions of thrombin. It corresponds to the PAR1 tethered ligand, facilitating selective activatio... |
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T36288 |
Protease-Activated Receptor-1, PAR-1 Agonist TFA
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Protease-Activated Receptor-1 (PAR-1) Agonist TFA is a selective peptide that acts as an agonist for the proteinase-activated receptor-1 (PAR-1). Corresponding to the tethered ligand of PAR-1, this compound mimics the ac... |
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T7380 |
Protease-Activated Receptor-4
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Protease-activated Receptor
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Protease-Activated Receptor-4 is the proteinase-activated receptor-4 (PAR4) agonist, with Antiplatelet Therapy |
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T36289 |
Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA
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Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a peptide that acts as an agonist for the proteinase-activated receptor (PAR-3)[1]. |
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T36286 |
Protease-Activated Receptor-3 (PAR-3) (1-6), human
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TFRGAP-amide, human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells. |
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T1986L |
Atopaxar Hydrobromide
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Protease-activated Receptor
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Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome. |
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T1986 |
Atopaxar
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E5555,ER-172594-00 |
Protease-activated Receptor
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Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome. |
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T1893 |
Parmodulin 2
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ML 161 |
Protease-activated Receptor
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Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb... |
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T64285 |
Protease-Activated Receptor-1 antagonist 2
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Protease-Activated Receptor-1 antagonist 2 is a selective, orally active protease-activated receptor-1 (PAR-1) antagonist (IC50: 7 nM). It has shown good pharmacokinetic properties and can be used for studies related to ... |
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TQ0012 |
AZ3451
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Protease-activated Receptor
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AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM). |
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T7137 |
I-191
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Protease-activated Receptor
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I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells. |
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T62507 |
Protease-Activated Receptor-1 antagonist 1
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Protease-Activated Receptor-1 antagonist 1 (Compound 13) is a protease-activated receptor 1 (PAR-1) antagonist with an IC50 of 3 nM obtained by the FLIPR technique. antagonist 1 can be used to study thrombotic cardiovasc... |
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T63382 |
Protease-Activated Receptor-1 antagonist 3
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Protease-Activated Receptor-1 antagonist 3 is a potent antagonist (IC50: 7 nM) of Protease-Activated Receptor 1protease-activated receptor-1. antagonist 3 exhibits binding affinity to hERG K+ channels (IC50: 9 μM). |
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T74266 |
Protease-Activated Receptor-1 antagonist 2
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Protease-Activated Receptor-1 Antagonist 2 is an orally active antagonist of protease-activated receptor-1 (PAR-1), demonstrating significant potency with an IC 50 of 7 nM. It exhibits favorable pharmacokinetic character... |
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TP1046L |
PAR-2 Activating Peptide acetate
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SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate |
Protease-activated Receptor
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PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2). |
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T2370 |
AC-55541
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AOB2796 |
Proteasome
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Protease-activated Receptor
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AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. |
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T7625 |
TRAP-6
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PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA) |
Protease-activated Receptor
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TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1). |
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T7013 |
Vorapaxar
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SCH 530348,MK-5348 |
Protease-activated Receptor
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Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM). |
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T75902 |
SLIGRL-NH2 TFA
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Protease-Activated Receptor-2 Activating Peptide TFA |
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SLIGRL-NH2 TFA, also known as Protease-Activated Receptor-2 Activating Peptide TFA, is a Protease-Activated Receptor-2 (PAR-2) agonist [1]. |
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TP1046 |
SLIGRL-NH2
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Protease-Activated Receptor-2 Activating Peptide |
Protease-activated Receptor
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SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a protease-activated receptor-2 (PAR-2) agonist that induces non-histaminergic pruritus. |
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T12870 |
SCH79797 dihydrochloride
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Apoptosis
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Others
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Protease-activated Receptor
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SCH79797 dihydrochloride is a selective antagonist of nonpeptide protease activated receptor 1 (PAR1). |
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T8917 |
PAR-2-IN-1
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IUN76750 |
Protease-activated Receptor
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PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects. |
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T3098 |
Vorapaxar sulfate
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SCH 530348 sulfate,Zontivity,vorapaxar monosulfate |
Protease-activated Receptor
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Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist. |
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TP1065 |
PAR-4 Agonist Peptide, amide TFA
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PAR-4-AP (TFA),AY-NH2 (TFA) |
Protease-activated Receptor
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PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)), is a selective activator of the proteinase-activated receptor-4 (PAR-4), demonstrating specificity by not influencing PAR-1 or PAR-2, and its activity can be inhibited b... |
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T7623 |
PAR-4 Agonist Peptide, amide
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AY-NH2,PAR-4 Agonist Peptide, amide(2TFA),PAR-4-AP |
Protease-activated Receptor
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PAR-4 Agonist Peptide, amide (AY-NH2) is an agonist of proteinase-activated receptor-4 (PAR-4). |
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T4186 |
AC-264613
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AC264613 |
Protease-activated Receptor
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AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macropha... |
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T7573 |
TFLLR-NH2
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TFLLR-NH2(2TFA) |
Protease-activated Receptor
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TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM). |
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T7496 |
Thrombin Receptor Activator for Peptide 5 (TRAP-5)
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Thrombin Receptor Activator for Peptide |
Protease-activated Receptor
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Thrombin Receptor Activator for Peptide 5 (TRAP-5), also known as Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), is employed in coronary heart disease (CHD) research. |
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T63966 |
BMS-986141
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UDM-003183 |
Protease-activated Receptor
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BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614 exhibits significant antithrombotic effects. |
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TP1378 |
2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
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2-Furoyl-LIGRLO-amide |
Protease-activated Receptor
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2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist. |
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T21699L |
VKGILS-NH2 Acetate
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VKGILS-NH2 Acetate (942413-05-0 Free base) |
Protease-activated Receptor
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VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist. |
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TP1904L |
FSLLRY-NH2 TFA(245329-02-6 free base)
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Protease-activated Receptor
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FSLLRY-NH2 TFA is a is a protease-activated receptor 2 (PAR2) inhibitor. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in iso... |
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T22792 |
FR-171113
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Others
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Protease-activated receptor 1 antagonist |
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T23282 |
RWJ-56110
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Others
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protease-activated receptor-1 (PAR1) antagonist |
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T27406 |
GB83
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GB-83,GB 83 |
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GB83 is a selective human protease activated receptor 2 (PAR2) antagonist. |
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T75871 |
FSLLRY-NH2 TFA
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FSLLRY-NH2 TFA is a protease-activated receptor 2 (PAR2) inhibitor [1] . |
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T17200 |
UDM-001651
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Others
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UDM-001651 is an effective and orally bioavailable protease-activated receptor 4 antagonists (IC50=4 nM; Kd=1.4 nM). UDM-001651 displays antiplatelet potency (IC50=25 nM) in a γ-thrombin-induced platelet-rich plasma aggr... |
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T11369 |
GB-110
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Others
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GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM. GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. |
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T73854 |
GB-110 hydrochloride
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GB-110 hydrochloride, a potent and orally active nonpeptidic agonist of the protease-activated receptor 2 (PAR2), selectively triggers PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM [1]. |
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T80111 |
TRAP-5 amide
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TRAP-5 amide is a peptide agonist for protease-activated receptor 1 (PAR 1) [1]. |
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T11369L |
GB-110 hydrochloride (1252806-70-4 free base)
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GB-110 hydrochloride |
Others
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GB-110 hydrochloride selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM. GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR... |
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T14684 |
BMS-986120
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Others
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T22933 |
LRGILS-NH2
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Others
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LRGILS-NH2 is a reversed amino acid sequence control peptide for SLIGRL-NH2, a protease-activated receptor-2 (PAR2) agonist that facilitates gastrointestinal transit in vivo. |
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T75904 |
PAR 4 (1-6) (TFA)
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PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide derived from protease-activated receptor 4 (PAR 4), serves as a specific agonist for PAR 4. This fragment of PAR 4 [1] exhibits targeted activation properties. |
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TP1965 |
Parstatin(human)
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Parstatin (human) |
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Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 3 μM), and induces cell cycle arrest. Promotes activation... |
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TP1966 |
Parstatin(mouse)
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Parstatin (mouse) |
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Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 20 μM), and induces cell cycle arrest. Promotes activatio... |
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T75903 |
VKGILS-NH2 TFA
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VKGILS-NH2 TFA is a reversed-sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist. It demonstrates no impact on cellular DNA synthesis [1] [2]. |
